原著論文(東原)

  1. 81. Sakurai, T., Nakagawa, T., Mitsuno, H., Mori, H., Endo, Y., Tanoue, S., Yasukochi, Y., Touhara, K.*, and Nishioka, T.*
    "Identification and functional characterization of a sex pheromone receptor in the silkmoth Bombyx mori"
    Proc. Natl. Acad. Sci. U.S.A. 101, 16653-16658 (2004)
  2. 82. Fukuda, N., Yomogida, K., Okabe, M., and Touhara, K.*
    "Functional characterization of a mouse testicular olfactory receptor and its role in chemosensing and regulation of sperm motility"
    J. Cell Sci. 117, 5835-5845 (2004)
  3. 83. Katada, S., Tanaka, M., and Touhara, K.*
    "Structural determinants for membrane trafficking and G protein selectivity of a mouse olfactory receptor"
    J. Neurochem. 90, 1453-1463 (2004)
  4. 84. Oka, Y., Omura, M., Kataoka, H., and Touhara, K.*
    "Olfactory receptor antagonism between odorants"
    EMBO J. 23, 120-126 (2004)
  5. 85. Omura, M., Sekine, H., Shimizu, T., Kataoka, H., and Touhara, K.*
    "In situ Ca2+ imaging of odor responses in a coronal olfactory epithelium"
    NeuroReport 14, 1123-1127 (2003)
  6. 86. Katada, S., Nakagawa, T., Kataoka, H., and Touhara, K.*
    "Odorant response assays for a heterologously expressed olfactory receptor"
    Biochem. Biophys. Res. Commu. 305, 964-969 (2003)
  7. 87. Touhara, K.*
    "Odor discrimination by G protein-coupled olfactory receptors"
    Microscopic Research and Technology 58, 135-141 (2002)
  8. 88. Kajiya, K., Inaki, K., Tanaka, M., Haga, T., Kataoka, H., and Touhara, K.*
    "Molecular bases of odor discrimination: reconstitution of olfactory receptors that recognize overlapping sets of odorants"
    J. Neuroscience 21, 6018-6025 (2001)
  9. 89. Touhara, K.*
    "Functional cloning and reconstitution of vertebrate odorant receptors"
    Life Sciences 68, 2199-2206 (2001)
  10. 90. Tanaka, M., Konishi, H., Touhara, K., Sakane, F., Hirata, M., Ono, Y., and Kikkawa, U.
    " Identification of myosin II as a binding protein to the PH domain of protein kinase B"
    Biochem. Biophys. Res. Comm. >255, 169-174 (1999)
  11. 91. Touhara, K.*, Sengoku, S., Inaki, K., Tsuboi, A., Hirono, J., Sato, T., Sakano, H., and Haga, T.
    "Functional identification and reconstitution of an odorant receptor in single olfactory neurons"
    Proc. Natl. Acad. Sci. USA 96, 4040-4045 (1999)
  12. 92. Touhara, K.*
    "Effects of mutations in pleckstrin homology domain on b-adrenergic receptor kinase activity in intact cells"
    Biochem. Biophys. Res. Comm. >252, 669-674 (1998)
  13. 93. Touhara, K.*
    "Binding of multiple ligands to pleckstrin homology domain regulates membrane translocation and enzyme activity of b-adrenergic receptor kinase"
    FEBS Letters 417, 243-248 (1997)
  14. 94. Ohmichi, M., Koike, K., Kimura, A., Masuhara, K., Ikegami, H., Ikebuchi, Y., Kanzaki, T., Touhara, K., Sakaue, M., Kobayashi, Y., Akabane, M., Miyake, A., and Murata, K.,
    "Role of Mitogen-activated protein kinase pathway in prostaglandin F2a-induced rat puerperal uterine contraction"
    Endocrinology 138, 3103-3111 (1997)
  15. 95. Boekhoff, I., Touhara, K., Danner, S., Inglese, J., Lohse, M.J., Breer, H., and Lefkowitz, R.J.
    "Phosducin: potential role in modulation of olfactory signaling"
    J. Biol. Chem. 272, 4606-4612 (1997)
  16. 96. Touhara, K., Wojtasek, W., and Prestwich, G.D.
    "In vitro modeling of the ternary interaction in juvenile hormone metabolism"
    Arch. Insect Biochem. Physiol.32, 399-406 (1996)
  17. 97. Yokozeki, T., Kuribara, H., Katada, T., Touhara, K., and Kanaho, Y.
    "Rat brain phospholipase D specifically binds to phosphatidylinositol 4, 5-bisphosphate"
    J. Neurochemistry66, 1234-1239 (1996)
  18. 98. Touhara, K., Hawes, B.E., van Biesen, T., and Lefkowitz, R.J.
    "G protein bg subunits stimulate phosphorylation of Shc adaptor protein"
    Proc. Natl. Acad. Sci. USA92, 9284-9287 (1995)
  19. 99. van Biesen, T., Hawes, B.E., Luttrell, D.K., Krueger, K., Touhara, K., Porfiri, E., Sakaue, M., Luttrell, L.M. and Lefkowitz, R.J.
    "Gbg and receptor tyrosine kinase mediated MAP kinase activation via a common signaling pathway"
    Nature376, 781-784 (1995)
  20. 100. Touhara, K., Koch, W.J., Hawes, B.E., and Lefkowitz, R.J.
    "Mutational analysis of the pleckstrin homology domain of b-adrenergic receptor kinase: differential effects on Gbg and phosphatidylinositol-4,5-bisphosphate binding"
    J. Biol. Chem. 270, 17000-17005 (1995)